Linoleic acid stimulates gluconeogenesis via Ca /PLC, cPLA2, and PPAR pathways through GPR40 in primary cultured chicken hepatocytes
نویسندگان
چکیده
Han Na Suh, Huang Thi Huong, Chang Hun Song, Jang Hern Lee, and Ho Jae Han Department of Veterinary Physiology, Biotherapy Human Resources Center (BK21), College of Veterinary Medicine, Chonnam National University, Gwangju, Korea; Department of Obstetrics and Gynecology, Chosun University Medical School, Gwangju, Korea; and Department of Veterinary Physiology, College of Veterinary Medicine, Seoul National University, Seoul, Korea
منابع مشابه
Linoleic acid stimulates gluconeogenesis via Ca2+/PLC, cPLA2, and PPAR pathways through GPR40 in primary cultured chicken hepatocytes.
Fatty acids serve vital functions as sources of energy, building materials for cellular structures, and modulators of physiological responses. Therefore, this study examined the effect of linoleic acid on glucose production and its related signal pathways in primary cultured chicken hepatocytes. Linoleic acid (double-unsaturated, long chain) increased glucose production in a dose (> or =10(-4) ...
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Fujiwara, Ken, Fumihiko Maekawa, and Toshihiko Yada. Oleic acid interacts with GPR40 to induce Ca signaling in rat islet -cells: mediation by PLC and L-type Ca channel and link to insulin release. Am J Physiol Endocrinol Metab 289: E670–E677, 2005. First published May 24, 2005; doi:10.1152/ajpendo.00035.2005.—It has long been thought that long-chain free fatty acids (FFAs) stimulate insulin sec...
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